RESEARCH ARTICLE
The Use of Spectral-Domain Optical Coherence Tomography to Detect Glaucoma Progression
Ricardo Y Abe 1, 2, Carolina P.B Gracitelli 1, 3, Felipe A Medeiros*, 1
Article Information
Identifiers and Pagination:
Year: 2015Volume: 9
First Page: 78
Last Page: 88
Publisher ID: TOOPHTJ-9-78
DOI: 10.2174/1874364101509010078
Article History:
Received Date: 28/3/2015Revision Received Date: 30/3/2015
Acceptance Date: 30/3/2015
Electronic publication date: 15 /5/2015
Collection year: 2015

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Abstract
Detection of progression and measurement of rates of change is at the core of glaucoma management, and the use of Spectral Domain Optical Coherence Tomography (SD-OCT) has significantly improved our ability to evaluate change in the disease. In this review, we critically assess the existing literature on the use of SD-OCT for detecting glaucoma progression and estimating rates of change. We discuss aspects related to the reproducibility of measurements, their accuracy to detect longitudinal change over time, and the effect of aging on the ability to detect progression. In addition, we discuss recent studies evaluating the use of combined structure and function approaches to improve detection of glaucoma progression.