REVIEW ARTICLE

A Single Drop in the Eye – Effects on the Whole Body?

The Open Ophthalmology Journal 31 Oct 2017 REVIEW ARTICLE DOI: 10.2174/1874364101711010305

Abstract

Introduction:

Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in some cases even life-threatening, effects of commonly used eye drops.

Conclusion:

This brief review outlines the routes of systemic absorption and the kinetics of active components present in eye drops, and identifies the clinically relevant systemic adverse effects.

Keywords: Single drop , Ophthalmic drugs , Eye , Body , Kinetics , Ocular drugs .
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