RESEARCH ARTICLE
Single-Session Low Duration Panretinal Photocoagulation Using Conventional Laser on Central Subfield Macular Thickness in Diabetic Retinopathy
Arief S Kartasasmita*, Prettyla Yollamanda, Grimaldi Ihsan, Rova Virgana
Article Information
Identifiers and Pagination:
Year: 2018Volume: 12
First Page: 308
Last Page: 313
Publisher ID: TOOPHTJ-12-308
DOI: 10.2174/1874364101812010308
Article History:
Received Date: 10/6/2018Revision Received Date: 25/10/2018
Acceptance Date: 3/11/2018
Electronic publication date: 28/12/2018
Collection year: 2018
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Objective:
To compare the change in central subfield macular thickness following single-session and multiple-session laser panretinal photocoagulation in subjects with diabetic retinopathy.
Methods:
A single-center, randomized controlled trial study was performed on 28 eyes of 16 patients with severe non-proliferative diabetic retinopathy or proliferative diabetic retinopathy. Eyes were randomly assigned for treatment with panretinal photocoagulation performed either in single-session or multiple-session divided into three sessions during two-week period. Central subfield macular thickness was quantified using spectral domain optical coherence tomography and changes at four weeks follow-up were compared to the baseline measurement.
Result:
Mean baseline central subfield macular thickness of 12 eyes underwent single-session and 16 eyes underwent multiple-session panretinal photocoagulation were 342.91+109.51 micrometers and 354+171.79 micrometers (p> .05), respectively. Mean post laser central subfield macular thickness in the single-session group was 305.83+ 81.95 micrometers and 389.75 + 229.51 micrometers in the multiple-session group (p > .05). Mean central subfield macular thickness changes four weeks post laser was 37.08 + 94.21 micrometers for eyes treated with single-session and -35.75+123.62 micrometers for the multiple-session treated eyes (p = .101).
Conclusion:
There was no significant difference in change of central subfield macular thickness at four weeks post laser from treatment with single-session and multiple-session panretinal photocoagulation. Single-session panretinal photocoagulation can be used as effective multiple-session panretinal photocoagulation for the treatment of diabetic retinopathy.
