RESEARCH ARTICLE


Laser Vitreolysis for Vitreous Opacities: A Prospective Study



Adam Ernest1, Miroslav Veith1, Jakub Dítě1, Jana Vránová2, Peter Mojžiš1, David P. Piñero3, *
1 Department of Ophthalmology, Royal Vinohrady University Hospital and The Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
2 Department of Medical Biophysics and Informatics, The Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
3 Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain


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Creative Commons License
© 2023 Ernst et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Optics, Pharmacology and Anatomy, University of Alicante, Crta San Vicente del Raspeig s/n 03690 San Vicente del Raspeig Alicante, Spain; Tel: +34965903400; E-mail: david.pinyero@ua.es


Abstract

Aim:

The aim of this study is to evaluate the efficacy and safety of a YAG laser vitreolysis procedure used to remove bothersome vitreous opacities/floaters.

Methods:

The prospective clinical study included 42 eyes of 35 patients (age 32-81 years) with vitreous opacities generating visual disturbances. All patients were treated using the Ellex - Ultra Q Reflex YAG laser and underwent a complete eye examination before the laser vitreolysis and at 1, 3 and 6 months after the intervention. Changes in corrected distance visual acuity (CDVA), central retinal thickness (CRT), intraocular pressure (IOP) and patient’s subjective perception of disturbances were analysed.

Results:

The average number of laser shots was 118 (6 - 310 shots), with a total average energy of 3.8 mJ per laser shot (2.2 - 9 mJ). The laser intervention was performed only once in a total of 31 eyes (73.8%), whereas it was necessary to perform the intervention twice in 10 cases (23.8%). No significant differences in CDVA were detected during the whole follow-up (p>0.40). No significant changes were found either in CRT (p>0.32). Concerning IOP (p<0.001), it was reduced significantly immediately after the intervention, returning to the pre-intervention level afterwards. The analysis of the responses to the questionnaire revealed that there was a mean improvement in subjective visual symptoms according to patients of 71%. No complications were detected in the sample during the follow-up.

Conclusion:

Laser vitreolysis is a minimally invasive treatment, allowing a complete or partial elimination of vitreous opacities and leading to alleviation of patient’s disturbances.

Keywords: Posterior vitreous membrane, Vitreous opacities, Floaters, Laser, Vitreolysis, Posterior vitreous detachment.