Regression of Urrets-Zavalia Syndrome After Deep Lamellar Keratoplasty for Keratoconus: A Case Study

Leopoldo Spadea*, Mariangela Viola, Giovanna Viola
Eye Clinic, San Salvatore Hospital, Surgical Science Department, University of L'Aquila, L’Aquila, Italy

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 2729
Abstract HTML Views: 1731
PDF Downloads: 645
Total Views/Downloads: 5105
Unique Statistics:

Full-Text HTML Views: 1231
Abstract HTML Views: 1027
PDF Downloads: 401
Total Views/Downloads: 2659

Creative Commons License
© Spadea et al.; Licensee Bentham Open.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Via Benozzo Gozzoli 34, 00142 Rome, Italy; Tel: +39/0862/319671; Fax: +39/0862/319672; E-mail:


We report a case of pharmacologic regression of Urrets-Zavalia syndrome, following deep lamellar keratoplasty for severe keratoconus. Sympatholytic and parasympathomimetic drops were administered and a progressive reduction of mydriasis and restoring of pupillary kinetics were observed. Four years after surgery, it was resulting in only slight residual anisocoria.

Keywords: Dapiprazole, DLK, keratoconus, pilocarpine, Urrets-Zavalia syndrome.