Use of Intravitreal Triamcinolone in the Treatment of Macular Edema Related to Retinal Vein Occlusion

The Open Ophthalmology Journal 7 Apr 2008 RESEARCH ARTICLE DOI: 10.2174/1874364100802010068


Objective: To analyze the increasing trend of intravitreal triamcinolone (IVTA) use in the treatment of retinal vein occlusion-related macular edema.

Methods:We performed MEDLINE/PUBMED searches (September 1984 - December 2007) to identify articles containing the keywords macular edema and triamcinolone. Case reports, reviews and abstracts were identified from references in the reviewed literature. This review focuses on literature published during the past 7 years with more than two-thirds of the articles that we reviewed being printed during the past 5 years. These reports analyzed the success of IVTA in the treatment of macular edema over a 12 month course of time.

Results: The majority of studies suggested promising results for short time periods (4-6 months) after IVTA treatments. However, long term results were not encouraging.

Conclusions: The success of IVTA therapy for short durations has been the impetus for development of sustained release devices to be used in the treatment of macular edema associated with various retinal diseases including edema related to retinal vein occlusion.

Keywords: Intravitreal triamcinolone, macular edema, retinal vein occlusion.
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