RESEARCH ARTICLE


Additional Applications of Corneal Cross Linking



Vassilios Kozobolis*, Georgios Labiris, Maria Gkika , Haris Sideroudi
Eye Institute of Thrace (EIT), Democritus University, Alexandroupolis, Greece


Article Metrics

CrossRef Citations:
0
Total Statistics:

Full-Text HTML Views: 758
Abstract HTML Views: 912
PDF Downloads: 140
Total Views/Downloads: 1810
Unique Statistics:

Full-Text HTML Views: 472
Abstract HTML Views: 530
PDF Downloads: 98
Total Views/Downloads: 1100



© Kozobolis et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Eye Institute of Thrace, Democritus University, Department of Medicine, Alexandroupolis, Greece; Tel: +302551030990; Fax: 302551039891; E-mail: vkozompo@med.duth.gr


Abstract

Corneal collagen cross-linking (CxL) is a prevalent surgical method for the management of keratoconus. However, literature suggests that, further to keratoconus, CxL has a beneficial impact on a series of corneal related diseases and states.

This article attempts to provide a contemporary review for all additional applications of CxL. Specifically, it outlines the most recent studies that demonstrate the beneficial impact of CxL for iatrogenic ectasias, pellucid marginal degeneration, infectious keratitis, bullous keratitopathy, and for ulcerative keratitis.

The outcome of this review indicates that CxL could serve as a primary or adjuvant therapeutic modality for all aforementioned corneal-related pathologic states.

Keywords: Corneal collagen cross-linking, review, iatrogenic ectasias, pellucid marginal degeneration, bullous keratopathy, infectious keratitis.