Effectiveness of Scraping and Mitomycin C to Treat Haze After Myopic Photorefractive Keratectomy

Leopoldo Spadea*, Valerio Verrecchia
Department of Surgical Sciences, University of L'Aquila, Eye Clinic, L’Aquila, Italy

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© Spadea and Verrecchia; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Surgical Sciences, University of L'Aquila, Eye Clinic, L’Aquila, Via Benozzo Gozzoli 34, 00142 Rome, Italy; Tel: +39/0862/319671; Fax: +39/0862/434958; E-mail:


To report the possibility of post myopic photorefractive keratectomy (PRK) haze treatment in a patient with expressed reluctance for any additional laser therapy. Seven months after bilateral PRK with subsequent development of corneal haze and refractive regression in both eyes, a 37-old-year male patient presented a best-spectacle corrected visual acuity (BSCVA) of 20/30 in the right eye and of 20/22 in the left eye. Both eyes were sequentially treated by scraping the stromal surface and application of mitomycin C (MMC) for 2 minutes. Both eyes had significant improvement in corneal transparency. Eighteen months after this treatment BSCVA had improved to 20/20 in each eye. No toxic effects were observed during either re-epithelialization or follow-up periods. In conclusion scraping and application of MMC could be considered a good tool in the treatment of selected cases of haze after myopic PRK, especially with patients that are reluctant to undergo a secondary laser procedure.

Keywords: Mitomycin C, Haze, PRK, Scraping.