Presumed Pyogenic Granuloma Associated with Intravitreal Anti-Vascular Endothelial Growth Factor Therapy

Jesse J Jung 1, 2, Kara E Della Torre 1, 2, 3, Millie R Fell 1, Christopher C Teng 1, 4, K Bailey Freund*, 1, 2, 3, 5
1 Department of Ophthalmology, New York University School of Medicine, New York, NY, USA
2 LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Institute, New York, NY, USA
3 Vitreous, Retina, Macula Consultants of New York, New York, NY, USA
4 Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY, USA
5 Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA

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© Jung et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http: // which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the 460 Park Avenue, Fifth Floor, New York, NY 10022, USA; Tel: 212-861-9797; Fax: 212-628-0698; E-mail:


To report a case of a presumed pyogenic granuloma at the site of multiple intravitreal anti-Vascular Endothelial Growth Factor (VEGF) injections. Intravitreal anti-VEGF injections can be complicated by a localized reaction of the conjunctiva.

Keywords: Ranibizumab (Lucentis), age-related macular degeneration, pyogenic granuloma, nodule, inflammation.