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Death by Water: Precautionary Water Submersion for Intravitreal Injection of Retinoblastoma Eyes
Jasmine H Francis, *
, 1
Xiaoliang L Xu 2
Y. Pierre Gobin 3
Brian P Marr 1 , 4
Scott E Brodie 5
David H Abramson 1 , 4
Authors Info & Affiliations
, 1
Xiaoliang L Xu 2
Y. Pierre Gobin 3
Brian P Marr 1 , 4
Scott E Brodie 5
David H Abramson 1 , 4
Authors Info & Affiliations
Abstract
There is growing interest in intravitreal injections of chemotherapy for retinoblastoma. However, concerns for potential tumor seeding through the needle track has prompted the use of risk-reducing precautionary methods. Presented here is a novel technique, which can be easily replicated, requires minimal sophisticated equipment and with laboratory data supporting its concept. Sterile distilled water submersion for 3 minutes renders retinoblastoma cells nonviable and can be employed as a precautionary method following intravitreal injection in the technique described here.
Keywords: Cancer, chemotherapy, distilled water, fine needle aspiration, intravitreal injection, melphalan, retinoblastoma, water.
