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RESEARCH ARTICLE

Death by Water: Precautionary Water Submersion for Intravitreal Injection of Retinoblastoma Eyes

The Open Ophthalmology Journal 16 May 2014 RESEARCH ARTICLE DOI: 10.2174/1874364101408010007

Abstract

There is growing interest in intravitreal injections of chemotherapy for retinoblastoma. However, concerns for potential tumor seeding through the needle track has prompted the use of risk-reducing precautionary methods. Presented here is a novel technique, which can be easily replicated, requires minimal sophisticated equipment and with laboratory data supporting its concept. Sterile distilled water submersion for 3 minutes renders retinoblastoma cells nonviable and can be employed as a precautionary method following intravitreal injection in the technique described here.

Keywords: Cancer, chemotherapy, distilled water, fine needle aspiration, intravitreal injection, melphalan, retinoblastoma, water.
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