A Case of Anterior Chamber Cholesterolosis Due to Coats' Disease and a Review of Reported Cases

Andrew W. Stacey1, *, Melissa Borri2, Sonia De Francesco2, Angela S. Antenore2, Felice Menicacci2, Theodora Hadjistilianou2
1 Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA
2 Unit of Ophthalmology, University of Siena, Policlinico "Santa Maria alle Scotte" Siena, Italy

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Creative Commons License
© Stacey et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Ophthalmology and Visual Sciences, University of Michigan 1000 Wall Street Ann Arbor, MI 48103, USA; Tel: 614-598-3420; E-mail:



To present the case of an 18 month old boy with Coats' disease who was found to have anterior chamber cholesterolosis.


Case presentation and review of reported cases.


An 18 month old boy presented with unilateral stage 3B Coats' disease without other clinical findings. Two weeks after presentation he returned with xanthocoria due to anterior chamber cholesterolosis. He subsequently developed hyphema, neovascular glaucoma, and was enucleated. His case is compared to all previously reported cases of Coats' disease leading to anterior chamber cholesterolosis.


The presentation of anterior chamber cholesterolosis in Coats' disease can range from the incidental finding in an asymptomatic patient to acute angle closure glaucoma with pain and acutely decreased vision. Clinicians should be aware of this potential complication of Coats' disease as it denotes a poor visual prognosis.

Keywords: Cholesterolosis, coats' disease, prognosis, anterior chamber.