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CASE REPORT

First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty

The Open Ophthalmology Journal 19 June 2017 CASE REPORT DOI: 10.2174/1874364101711010117

Abstract

Purpose:

To report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK)

Methods:

A retrospective case report.

Results:

A patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed fungal endophthalmitis that was treated medically with multiple injections of voriconazole and amphotericin. Medical treatment was unable to clear the infection and removal of the donor material was required. Following removal the infection subsided.

Conclusion:

Candida interface keratitis and endophthalmitis can occur following DMEK and may be difficult to treat medically. Early removal of the donor material should be considered.

Keywords: Candida, candida albicans, candida glabrata, fungal keratitis, descemet stripping endothelial keratoplasty, DMEK, corneal donor rim contamination.
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