First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty

Thompson, Matthew; Carli, David

First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty

Matthew Thompson^{1, *}, David Carli²

¹ Tower Clock Eye Center 1087 W Mason St. Green Bay, WI, 54303, USA

² Medical Student Des Moines University, 3200 Grand Ave Des Moines, IA 50312, USA

Article Information

Identifiers and Pagination:

Year: 2017
Volume: 11
First Page: 117
Last Page: 121
Publisher ID: TOOPHTJ-11-117
DOI: 10.2174/1874364101711010117

Article History:

Received Date: 03/01/2017
Revision Received Date: 13/02/2017
Acceptance Date: 04/04/2017
Electronic publication date: 19/06/2017
Collection year: 2017

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© 2017 Thompson and Carli.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* Address correspondence to this author at the Tower Clock Eye Center, 1087 W Mason St., Green Bay WI, 54303, USA; Tel: 920-499-3102; Fax: 920-499-9636; E-mail: Matthewt62@yahoo.com

Purpose:

To report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK)

Methods:

A retrospective case report.

Results:

A patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed fungal endophthalmitis that was treated medically with multiple injections of voriconazole and amphotericin. Medical treatment was unable to clear the infection and removal of the donor material was required. Following removal the infection subsided.

Conclusion:

Candida interface keratitis and endophthalmitis can occur following DMEK and may be difficult to treat medically. Early removal of the donor material should be considered.

Keywords: Candida, candida albicans, candida glabrata, fungal keratitis, descemet stripping endothelial keratoplasty, DMEK, corneal donor rim contamination.

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CASE REPORT

First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty

Article Information

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Article History:

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Unique Statistics:

Abstract

Purpose:

Methods:

Results:

Conclusion:

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