Magnetic Resonance Imaging in Case of Cortical Apex Syndrome Caused by Varicella Zoster Virus

Suguru Shirato1, Toshiyuki Oshitari*, 1, 2, Katsuhiro Hanawa1, Emiko Adachi-Usami1
1 Department of Ophthalmology, Center for Sensory Organ Diseases, Sannoh Medical Center, Chiba, Japan
2 Department of Ophthalmology, Kimitsu Central Hospital, Kisarazu, Japan

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© Shirato et al.; Licensee Bentham Open.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Department of Ophthalmology, Kimitsu Central Hospital, Sakurai 1010, Kisarazu City 292-0822, Chiba, Japan; Tel: 81-428-36-1071 Fax: 81-438-36-3867 E-mail:


We present a case of orbital apex syndrome that developed after a re-activation of varicella zoster virus. The magnetic resonance imaging showed signs of a diffuse inflammation of the ipsilateral orbital cavity, external ocular muscles and optic nerve. Pattern visually evoked cortical potentials were non-recordable by stimulating the affected eye.

Keywords: Orbital apex syndrome, varicella zoster virus, magnetic resonance imaging, visually evoked cortical potentials.