Acute Sclerokeratitis After Cataract Surgery: Treatment with Topical Use of Cyclosporine – A

K Doulas*, C Pantazopoulou, D Feretis
Department of Ophthalmology, General Hospital of Patras, Patras, Greece

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2008 Bentham Science Publishers Ltd.

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* Address correspondence to this author at the Department of Ophthalmology, General Hospital of Patras, Patras, Greece; E-mail:


We would like to report an interesting case of acute sclerokeratitis following cataract surgery treated with topical use of Cyclosporine-A. A 61-year old woman with a past history of scleritis in her right eye had an uneventful phaco surgery in her right eye for cataract removal via a corneoscleral incision. Eight months after the initial surgery the patient had a sudden decrease in her visual acquity in the right eye with marked inflammatory signs in the sclera and cornea adjacent to the entry-site of the phaco surgery. Initially the patient was treated with systemic corticosteroids but due to serious side effects topical cyclosporine-A was added instead. Five months later the patient has a significant improvement in terms of visual acquity with marked reduction in the inflammatory signs both in sclera and corneal tissue. We think that topical Cyclosporine-A with its potent immunomodulating effects seems to be of benefit in those cases where systemic corticosteroids are contraindicated or have serious side-effects.