RESEARCH ARTICLE
Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
L. Jay Katz*, Oana Stirbu, Garth Willis, Parul Ichhpujani
Article Information
Identifiers and Pagination:
Year: 2009Volume: 3
First Page: 75
Last Page: 76
Publisher ID: TOOPHTJ-3-75
DOI: 10.2174/1874364100903010075
Article History:
Received Date: 11/6/2009Revision Received Date: 23/7/2009
Acceptance Date: 31/8/2009
Electronic publication date: 25/9/2009
Collection year: 2009

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Abstract
We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. The intraocular pressure dropped dramatically from 48 mmHg to 10 mmHg postoperatively, negating the need for glaucoma surgery.