Abnormalities of Fundus Autofluorescence in Pigmented Paravenous Chorioretinal Atrophy

Hashimoto, Yuki; Kase, Satoru; Saito, Wataru; Ishida, Susumu

Abnormalities of Fundus Autofluorescence in Pigmented Paravenous Chorioretinal Atrophy

Yuki Hashimoto, Satoru Kase^*, Wataru Saito, Susumu Ishida

Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Nishi 7, Kita 15, Kita-ku, Sapporo 060-8638, Japan

Article Information

Identifiers and Pagination:

Year: 2012
Volume: 6
First Page: 125
Last Page: 128
Publisher ID: TOOPHTJ-6-125
DOI: 10.2174/1874364101206010125

Article History:

Received Date: 11/8/2012
Revision Received Date: 10/11/2012
Acceptance Date: 13/11/2012
Electronic publication date: 14/12/2012
Collection year: 2012

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© Hashimoto et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

^* Address correspondence to this author at the Department of Ophthalmology, Hokkaido University Graduate School of Medicine, N7, W15, Kita-ku, Sapporo, Hokkaido 060-8638, Japan; Tel: +81 11 706 5944; Fax: +81 11 706 5948; E-mail: kaseron@med.hokudai.ac.jp

The aim of this study is to investigate fundus autofluorescence (FAF) as well as fluorescein angiography (FA), indocyanine green angiography (IA), and optical coherence tomography (OCT) in a patient with pigmented paravenous chorioretinal atrophy (PPCRA). A funduscopic examination revealed chorioretinal atrophy along the paravenous area in both eyes. A marked bone spicule pigment clumping together with the atrophy was noted left eye. FA and IA showed a window defect and hypofluorescence, respectively, which exclusively corresponds to the atrophic area along the retinal vein area and the optic disc both eyes. FAF revealed geographic hypofluorescence along the paravenous and supranasal retinal areas. Hyperfluorescence was noted, which comparatively surrounded the hypofluorescence in the peripheral paravenous distribution. Hypofluorescence detected by FAF corresponded to the areas of retinal thinning and atrophy detected by OCT and FA. FAF is a useful examination in PPCRA, which can noninvasively demonstrate the distribution of deficit and dysfunction of retinal pigment epithelium.

Keywords: Fundus autofluorescence, pigmented paravenous chorioretinal atrophy, retinal pigment epithelium.

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CASE REPORT

Abnormalities of Fundus Autofluorescence in Pigmented Paravenous Chorioretinal Atrophy

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Abstract

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