RESEARCH ARTICLE


Long Term Results of Visual Field Progression Analysis in Open Angle Glaucoma Patients Under Treatment



Tolga Kocatürk*, 1, Sinan Bekmez 1, Merve Katrancı 2, Harun Çakmak , Volkan Dayanır 1
1 Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey
2 Department of Biostatistics, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey


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© Kocatürk et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey; Tel: 00 90 533 344 41 11; Fax: 00 90 256 214 64 95; E-mail: tolgakocaturk@gmail.com


Abstract

Purpose :

To evaluate visual field progression with trend and event analysis in open angle glaucoma patients under treatment.

Materials and Methods :

Fifteen year follow-up results of 408 eyes of 217 glaucoma patients who were followed at Adnan Menderes University, Department of Ophthalmology between 1998 and 2013 were analyzed retrospectively. Visual field data were collected for Mean Deviation (MD), Visual Field Index (VFI), and event occurrence.

Results :

There were 146 primary open-angle glaucoma (POAG), 123 pseudoexfoliative glaucoma (XFG) and 139 normal tension glaucoma (NTG) eyes. MD showed significant change in all diagnostic groups (p<0.001). The difference of VFI between first and last examinations were significantly different in POAG (p<0.001), and XFG (p<0.003) but not in NTG. VFI progression rates were -0.3, -0.43, and -0.2 % loss/year in treated POAG, XFG, and NTG, respectively. The number of empty triangles were statistically different between POAG-NTG (p=0.001), and XFG-NTG (p=0.002) groups. The number of half-filled (p=0.002), and full-filled (p=0.010) triangles were significantly different between XFG-NTG groups.

Conclusion :

Functional long-term follow-up of glaucoma patients can be monitored with visual field indices. We herein report our fifteen year follow-up results in open angle glaucoma.

Keywords: Glaucoma, normal tension, progression, primary open-angle, pseudoexfoliation.