RESEARCH ARTICLE
Surgically Induced Corneal Astigmatism Following Intravitreal Ranibizumab Injection
Tolga Kocatürk *, 1, Erol Erkan 1, Sait Eğrilmez2, Harun Çakmak1, Sema O. Dündar1, Volkan Dayanir1
Article Information
Identifiers and Pagination:
Year: 2015Volume: 9
First Page: 121
Last Page: 125
Publisher ID: TOOPHTJ-9-121
DOI: 10.2174/1874364101509010121
Article History:
Received Date: 27/1/2015Revision Received Date: 18/3/2015
Acceptance Date: 24/3/2015
Electronic publication date: 26/6/2015
Collection year: 2015

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Abstract
Purpose :
To evaluate surgically induced astigmatism (SIA) after an intravitreal ranibizumab (IVR) injection.
Methods :
Fifty eight eyes of 58 patients who underwent IVR injection due to age-related macular degeneration (wet form) or macular edema were included in this study. Patients’ pre- and postoperative detailed ophthalmologic examinations were done and topographic keratometric values (K1, K2) were noted. Pre- and postoperative measurements were compared.
Results :
The mean preoperative astigmatism of 0.87 Diopters (D) was found to be 0.95 D, 0.75 D, 0.82 D and 0.78 D on the 1st day, 3rd day, 1st week and 1st month, respectively. After injection, absolute change in astigmatism was found to be 0.08 D, 0.12 D, 0.05 D and 0.09 D on the 1st day, 3rd day, 1st week and 1st month, respectively. The absolute change in astigmatism seemed to be insignificant in terms of refractive analysis, however; when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, the mean value of induced astigmatism were found to be 0.33±0.22 D, 0.32±0.29 D, 0.41±0.37 D, 0.46±0.32 D on the 1st day, 3rd day, 1st week and on 1st month, respectively.
Conclusion :
Intravitreal injection is a minimally invasive ophthalmologic procedure, however; it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.