Surgically Induced Corneal Astigmatism Following Intravitreal Ranibizumab Injection

Kocatürk , Tolga; Erkan , Erol; Eğrilmez, Sait; Çakmak, Harun; Dündar, Sema O.; Dayanir, Volkan

Surgically Induced Corneal Astigmatism Following Intravitreal Ranibizumab Injection

Tolga Kocatürk ^{*, 1}, Erol Erkan ¹, Sait Eğrilmez², Harun Çakmak¹, Sema O. Dündar¹, Volkan Dayanir¹

¹ Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey

² Department of Ophthalmology, Faculty of Medicine, Ege University, Izmir, Turkey

³ Hospital Pulau Pinang, Jalan Residensi, 10990 Georgetown, Pulau Pinang, Malaysia

Article Information

Identifiers and Pagination:

Year: 2015
Volume: 9
First Page: 121
Last Page: 125
Publisher ID: TOOPHTJ-9-121
DOI: 10.2174/1874364101509010121

Article History:

Received Date: 27/1/2015
Revision Received Date: 18/3/2015
Acceptance Date: 24/3/2015
Electronic publication date: 26/6/2015
Collection year: 2015

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© Kocatürk et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

^* Address correspondence to this author at the Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey; Tel: 00 90 533 344 41 11; Fax: 00 90 256 214 64 95; E-mail: tolgakocaturk@gmail.com

Purpose :

To evaluate surgically induced astigmatism (SIA) after an intravitreal ranibizumab (IVR) injection.

Methods :

Fifty eight eyes of 58 patients who underwent IVR injection due to age-related macular degeneration (wet form) or macular edema were included in this study. Patients’ pre- and postoperative detailed ophthalmologic examinations were done and topographic keratometric values (K1, K2) were noted. Pre- and postoperative measurements were compared.

Results :

The mean preoperative astigmatism of 0.87 Diopters (D) was found to be 0.95 D, 0.75 D, 0.82 D and 0.78 D on the 1st day, 3rd day, 1st week and 1st month, respectively. After injection, absolute change in astigmatism was found to be 0.08 D, 0.12 D, 0.05 D and 0.09 D on the 1st day, 3rd day, 1st week and 1st month, respectively. The absolute change in astigmatism seemed to be insignificant in terms of refractive analysis, however; when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, the mean value of induced astigmatism were found to be 0.33±0.22 D, 0.32±0.29 D, 0.41±0.37 D, 0.46±0.32 D on the 1st day, 3rd day, 1st week and on 1st month, respectively.

Conclusion :

Intravitreal injection is a minimally invasive ophthalmologic procedure, however; it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.

Keywords: Intraocular pressure, intravitreal injection, ranibizumab, surgically induced astigmatism, vectorial analysis.

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RESEARCH ARTICLE

Surgically Induced Corneal Astigmatism Following Intravitreal Ranibizumab Injection

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