RESEARCH ARTICLE


Evaluation of Pollen Adhesion to Verofilcon-A Soft Contact Lenses



Tatsuya Mimura1, *, Hiroshi Fujishima2, Eichi Uchio3, Kazumi Fukagawa4, 5, Yuji Inoue1, Makoto Kawashima1, Kazuma Kitsu1, Atsushi Mizota1
1 Department of Ophthalmology, Teikyo University School of Medicine, Itabashi-ku, Tokyo, Japan.
2 Department of Ophthalmology, Tsurumi University School of Dental Medicine, Tsurumi-ku, Yokohama, Kanagawa, Japan.
3 Department of Ophthalmology, Fukuoka University School of Medicine, Jounan-ku, Fukuoka, Japan.
4 Ryogoku Eye Clinic, Sumida-ku, Tokyo, Japan
5 Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan


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Creative Commons License
© 2021 Mimura et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605 Japan; Tel: +81-3-3964-1211; Fax: +81-3-3964-1402; E-mail: mimurat-tky@umin.ac.jp


Abstract

Purpose:

A new 1-day disposable soft contact lens (SCL), verofilcon-A, constructed of silicone hydrogel material, has recently become available in Japan. This SCL has a very smooth surface produced by using the SMARTSURFACE ® Technology, and it was expected that pollen particles and protein components would not adhere easily to its surface. We examined the degree of pollen adhesion to the surface of the verofilcon-A material SCL and compared the results with those of other 1-day disposable SCLs (1DSCL).

Methods:

To determine the number of pollen grains attached to the surface of different types of SCLs, 0.01 mg/ml of cedar pollen solution was dropped onto the surface of 13 types of 1DSCL. After 24 h, each 1DSCL was rinsed in a shaker and washed five times with saline (n = 10 for each 1DSCL type). The number of pollen particles adhered to the 1DSCL and the percentage of surface area occupied by pollen was determined.

Results:

The number of pollen particles on the 1DSCLs ranged from 0 to 185 in the 200 × 200 µm area. The number of particles was lowest in the delefilcon-A and verofilcon-A SCLs with 0 particles, and the number was higher in the other 11 1DSCLs. The number of pollen particles was negatively correlated with the water content (r = −0.48), oxygen permeability (Dk; r = −0.43), oxygen transmissibility (r = −0.42), and center thickness (r = −0.33) of the 1DSCLs. The pollen adhesion area ranged from 0.0% to 3.1% and was lowest in the delefilcon-A and verofilcon-A 1DSCLs. There were significant differences in the pollen adhesion area between colored 1DSCLs (2.73 ± 1.97%) and clear 1DSCLs (1.03 ± 1.01%, P<0.001) and between hydroxyethyl methacrylate-based 1DSCLs (1.84 ± 1.45%) and silicone hydrogel-based 1DSCLs (0.05 ± 0.16%, P<0.001).

Conclusion:

These findings indicate that the verofilcon-A 1DSCL processed with SMARTSURFACE™ Technology is an excellent option for SCL users with allergic conjunctivitis during the high pollen season.

Keywords: Daily soft contact lens, Pollen, Silicone hydrogel, Verofilcon-A, Allergens, Conjunctivitis.